Press releases


Gene variant determines early or late onset of Huntington’s disease

5 May, 2015 - Karolinska Institutet

Researchers at Sweden’s Karolinska Institutet and the University of British Columbia, Canada, have identified a gene variant that influences whether Huntington’s disease breaks out earlier or later than expected. The findings, which are published in the scientific journal Nature Neuroscience, can contribute to improved diagnosis and disease-modifying therapies. A typical symptom of the inherited, progressive, […]

New knowledge on EphB signalling may improve treatment of intestinal cancers

2 April, 2015 - Karolinska Institutet

[PRESS RELEASE 4/2/2015] A new study led by researchers at Sweden’s Karolinska Institutet and Nanyang Technological University in Singapore, provides experimental evidence that a drug that inhibits the EphB-signalling pathway in the cell effectively can suppress the development of intestinal tumours. According to the investigators, this knowledge may be important in the design of new […]

Research on medical abortion and miscarriage may change international routines

27 March, 2015 - Karolinska Institutet

Two scientific studies led by researchers at Karolinska Institutet are expected to form the basis of new international recommendations for the treatment of miscarriages and medical abortions ― recommendations that may also lead to a change in clinical practice in Sweden. One of the studies, both of which are being published in the journal The Lancet, shows that it is possible to replace the clinical follow-up examinations recommended today with medical abortions that include a home pregnancy test. The other study shows that midwives can safely and effectively treat failed abortions and miscarriages in rural districts of Uganda.

How blood group O protects against malaria

10 March, 2015 - Karolinska Institutet

[PRESS RELEASE 3/10/2015] It has long been known that people with blood type O are protected from dying of severe malaria. In a study published in Nature Medicine, a team of Scandinavian scientists explains the mechanisms behind the protection that blood type O provides, and suggest that the selective pressure imposed by malaria may contribute to the variable global distribution of ABO blood groups in the human population.

Promising results for new Alzheimer therapy

13 February, 2015 - Karolinska Institutet

[PRESS RELEASE 02/13/2015] Scientists at Karolinska Institutet have evaluated a new Alzheimer’s therapy in which the patients receive an implant that stimulates the growth of a certain type of nerve cell. The results, which are published in the scientific journal ‘Alzheimer’s & Dementia’, suggest that the introduction of a nerve growth factor can prevent neuronal degradation in Alzheimer’s patients.

New therapeutic principle for Parkinsonian dyskinesia shows clinical effect

10 February, 2015 - Karolinska Institutet

[PRESS RELEASE 02/10/2015] Involuntary dyskinetic movements induced by treatment with levodopa (L-dopa) are a common problem for people with Parkinson’s disease. Now, however, researchers at Karolinska Institutet and Lund University in Sweden seem to be close to a novel therapy to this distressing side effect. A treatment study published in the scientific periodical Brain shows that a drug that stimulates certain serotonin receptors in the brain counteracts the dyskinesia causing effects of L-dopa.

Gut microbiota influences blood-brain barrier permeability

20 November, 2014 - Karolinska Institutet

[PRESS RELEASE 11/20/2014] A new study in mice, conducted by researchers at Sweden’s Karolinska Institutet together with colleagues in Singapore and the United States, shows that our natural gut-residing microbes can influence the integrity of the blood-brain barrier, which protects the brain from harmful substances in the blood. According to the authors, the findings provide experimental evidence that our indigenous microbes contribute to the mechanism that closes the blood-brain barrier before birth. The results also support previous observations that gut microbiota can impact brain development and function.

Young vessels rejuvenate aged insulin-producing beta cells

18 November, 2014 - Karolinska Institutet

[PRESS RELEASE 11/18/2014] A recent study published in the journal PNAS shows that young capillary vessels rejuvenate aged pancreatic islets. The finding challenges prevailing views on the causes of age-dependent impaired glucose balance regulation, a condition that often develops into diabetes type 2. The international research team behind the study now suggests that targeting inflammation and fibrosis in the small blood vessels of the pancreatic islets may offer a new way of treatment for age-dependent dysregulation of blood glucose levels.

Beta blockers could benefit patients with HFPEF

16 November, 2014 - Karolinska Institutet

[PRESS RELEASE 11/16/2014] A novel registry study from Karolinska Institutet in Sweden suggests that beta blockers may benefit also patients suffering from a relatively unknown form of heart failure called HFPEF, which today lacks well-established treatment. HFPEF involves an impaired ability of the heart to fill with blood, and affects nearly 2 per cent of the population. These new findings are being published in the scientific periodical JAMA.

Molecular time signalling controls stem cells during brain’s development

13 November, 2014 - Karolinska Institutet

[PRESS RELEASE 11/13/2014] Researchers at Karolinska Institutet in Sweden have succeeded in explaining how stem cells in the brain change to allow one type of stem cell to produce different cell types at different stages. In a study being published in the journal Neuron, researchers show that the signal molecule TGF-beta acts as a time signal that regulates the nerve stem cells’ potential at different stages of the brain’s development – knowledge that may be significant for future pharmaceutical development.